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| Injury Occurred | Franchise | Injury |
|---|---|---|
| Week 1 | NJR | LAN Belisario out until (suspension) Week 10 |
| Week 1 | SDQ | WAS Ramos out 1 away day Week 23 |
| Week 2 | MCM | WAS Morse out 3 home and 2 road days + DTD Week 11 |
| Week 2 | MOR | CLE Tomlin out 1 home day + DTD Week 13 |
| Week 2 | SFP | TB Fuld 3 home and 2 road days + DTD Week 18 |
| Week 2 | NJR | COL Nicasio out 3 home and 2 road days + DTD Week 20 |
| Week 2 | KAT | OAK Anderson out until + DTD Week 23 |
| Week 4 | GTY | PHI Utley out 1 road day + DTD Week 10 |
| Week 4 | PAD | BAL Hammel out 3 road and 2 home games + DTD Week 12 |
| Week 3 | HAV | LAN EllisM. out until Week 11 |
| Week 3 | HAV | MIL Marcum out 1 road day + DTD Week 9 |
| Week 4 | HAV | OAK McCarthy out until + DTD Week 17 |
| Week 5 | TRI | CHA Crain out 3 home and 1 road day + DTD Week 9 |
| Week 5 | KAT | ATL Hudson out 3 home and 2 road days + DTD Week 9 |
| Week 7 | CAN | CIN Mesoraco out 2 road days + DTD Week 9 |
| Week 7 | NJR | TOR Arencibia out until Week 14 |
| Week 7 | ODM | PHI Gavis out 3 road and 1 home day (suspension) Week 17 |
| Week 7 | NYK | LAN Beckett out 1 road day + DTD Week 10 |
| Week 7 | ODM | SEA Olivo out 2 home day + DTD Week 9 |
| Week 7 | HAV | OAK Colon out 3 road and 1 home day + DTD Week 9 |
| Week 7 | GTY | CLE Hannahan out 3 home day + DTD Week 9 |
| Week 8 | CAN | CAN CHN Campana (-2 hammy) 2 road days Week 9 |
| Week 8 | COU | LAA Haren out 2 road days + DTD Week 10 |
| Week 8 | BAL | DET Sanchez out 1 home day Week 9 |
| Week 8 | SDQ | SD Richard out 1 road day + DTD Week 9 |
| Week 8 | HAV | KC Dyson out 3 home days + DTD Week 9 |
| Week 8 | COU | PIT Bedard 3 home days and 2 road days + DTD Week 9 |
| Week 8 | TRI | TB Hellickson until + DTD Week 11 |
| Week 8 | BOW | ARI Collmenter out 1 home day Week 10 |
| Week 8 | KAT | DET Jackson (-2 hammy) 2 road days Week 10 |
| Week 8 | KAT | TOR Villanueva 1 road day + DTD Week 9 |
| Week 8 | PAD | MIN Doutmit out 1 road day + DTD Week 10 |